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mitotane will lessen the level or outcome of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of abemaciclib with robust CYP3A4 inducers reduces plasma focus of abemaciclib and its metabolites.Your healthcare company will prescribe a steroid-made up of mouthwash to work wit